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Ascorbic acid promotes cardiomyogenesis through SMAD1 signaling in differentiating mouse embryonic stem cells

Numerous groups have documented that Ascorbic Acid (AA) promotes cardiomyocyte differentiation from both mouse and human ESCs and iPSCs. AA is now considered indispensable for the routine production of hPSC-cardiomyocytes (CMs) using defined media; however, the mechanisms involved with the inductive...

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Detalles Bibliográficos
Autores principales:	Perino, Maria Grazia, Yamanaka, Satoshi, Riordon, Daniel R., Tarasova, Yelena, Boheler, Kenneth R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726630/ https://www.ncbi.nlm.nih.gov/pubmed/29232368 http://dx.doi.org/10.1371/journal.pone.0188569

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