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Lupeol and stigmasterol suppress tumor angiogenesis and inhibit cholangiocarcinoma growth in mice via downregulation of tumor necrosis factor-α

Lupeol and stigmasterol, major phytosterols in various herbal plants, possess anti-inflammatory activities and have been proposed as candidates for anti-cancer agents, but their molecular mechanisms are still unclear. Here, we investigated the effects of lupeol and stigmasterol on tumor and endothel...

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Detalles Bibliográficos
Autores principales: Kangsamaksin, Thaned, Chaithongyot, Supattra, Wootthichairangsan, Chanida, Hanchaina, Rattanavinan, Tangshewinsirikul, Chayada, Svasti, Jisnuson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726636/
https://www.ncbi.nlm.nih.gov/pubmed/29232409
http://dx.doi.org/10.1371/journal.pone.0189628