Cargando…
Immunodominant cytomegalovirus-specific CD8+ T-cell responses in sub-Saharan African populations
More than 90% of children in Africa are infected with cytomegalovirus (CMV) by the age of 12 months. However, the high-frequency, immunodominant CD8+ T-cell responses that control CMV infection have not been well studied in African populations. We therefore sought to define the immunodominant CMV-sp...
Autores principales: | Malik, Amna, Adland, Emily, Laker, Leana, Kløverpris, Henrik, Fardoos, Rabiah, Roider, Julia, Severinsen, Mai C., Chen, Fabian, Riddell, Lynn, Edwards, Anne, Buus, Søren, Jooste, Pieter, Matthews, Philippa C., Goulder, Philip J. R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726643/ https://www.ncbi.nlm.nih.gov/pubmed/29232408 http://dx.doi.org/10.1371/journal.pone.0189612 |
Ejemplares similares
-
Major TCR Repertoire Perturbation by Immunodominant HLA-B(*)44:03-Restricted CMV-Specific T Cells
por: Attaf, Meriem, et al.
Publicado: (2018) -
Recovery of effective HIV-specific CD4(+) T-cell activity following antiretroviral therapy in paediatric infection requires sustained suppression of viraemia
por: Adland, Emily, et al.
Publicado: (2018) -
Paediatric PARV4 infection in South Africa: relationship to age, maternal PARV4 status, and HIV infection
por: Matthews, Philippa, et al.
Publicado: (2014) -
Human Parvovirus 4 Infection among Mothers and Children in South Africa
por: Matthews, Philippa C., et al.
Publicado: (2015) -
A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape
por: Kløverpris, Henrik N, et al.
Publicado: (2015)