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Dependence of prevalence of contiguous pathways in proteins on structural complexity
Allostery is a regulatory mechanism in proteins where an effector molecule binds distal from an active site to modulate its activity. Allosteric signaling may occur via a continuous path of residues linking the active and allosteric sites, which has been suggested by large conformational changes evi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726733/ https://www.ncbi.nlm.nih.gov/pubmed/29232711 http://dx.doi.org/10.1371/journal.pone.0188616 |