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Data on the expression and role of TREM-1 in the development of in-stent restenosis

The data presented in this article are related to the research article entitled “Increased serum TREM-1 level is associated with in-stent restenosis, and activation of TREM-1 promotes inflammation, proliferation and migration in vascular smooth muscle cells” (Wang et al., 2017) [1], which demonstrat...

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Detalles Bibliográficos
Autores principales: Wang, Fang, Li, Chang, Ding, Feng Hua, Shen, Ying, Gao, Jie, Liu, Zhu Hui, Chen, Jia Wei, Zhang, Rui Yan, Shen, Wei Feng, Wang, Xiao Qun, Lu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726749/
https://www.ncbi.nlm.nih.gov/pubmed/29264376
http://dx.doi.org/10.1016/j.dib.2017.11.065
Descripción
Sumario:The data presented in this article are related to the research article entitled “Increased serum TREM-1 level is associated with in-stent restenosis, and activation of TREM-1 promotes inflammation, proliferation and migration in vascular smooth muscle cells” (Wang et al., 2017) [1], which demonstrated that TREM-1 is expressed on vascular smooth cells (VSMCs) and promotes inflammation, proliferation and migration in cultured VSMCs. In this dataset, the expression of TREM-1 in leukocytes and endothelial cells of carotid artery after ligation was evaluated. The effect of TREM-1 on stenosis was analyzed in cultured human saphenous veins (HSVs) that spontaneously undergo remodeling which involves VSMC proliferation and migration.