How B-Cell Receptor Repertoire Sequencing Can Be Enriched with Structural Antibody Data

Next-generation sequencing of immunoglobulin gene repertoires (Ig-seq) allows the investigation of large-scale antibody dynamics at a sequence level. However, structural information, a crucial descriptor of antibody binding capability, is not collected in Ig-seq protocols. Developing systematic rela...

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Detalles Bibliográficos
Autores principales: Kovaltsuk, Aleksandr, Krawczyk, Konrad, Galson, Jacob D., Kelly, Dominic F., Deane, Charlotte M., Trück, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727015/
https://www.ncbi.nlm.nih.gov/pubmed/29276518
http://dx.doi.org/10.3389/fimmu.2017.01753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727015/
https://www.ncbi.nlm.nih.gov/pubmed/29276518
http://dx.doi.org/10.3389/fimmu.2017.01753

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