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Myostatin Promotes Interleukin-1β Expression in Rheumatoid Arthritis Synovial Fibroblasts through Inhibition of miR-21-5p
Rheumatoid arthritis (RA) is characterized by the infiltration of a number of pro-inflammatory cytokines into synovial fluid and patients with RA often develop joint destruction and deficits in muscle mass. The growth factor myostatin is a key regulator linking muscle mass and bone structure. We sou...
Autores principales: | Hu, Sung-Lin, Chang, An-Chen, Huang, Chien-Chung, Tsai, Chun-Hao, Lin, Cheng-Chieh, Tang, Chih-Hsin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727021/ https://www.ncbi.nlm.nih.gov/pubmed/29276516 http://dx.doi.org/10.3389/fimmu.2017.01747 |
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