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Myostatin Promotes Interleukin-1β Expression in Rheumatoid Arthritis Synovial Fibroblasts through Inhibition of miR-21-5p

Rheumatoid arthritis (RA) is characterized by the infiltration of a number of pro-inflammatory cytokines into synovial fluid and patients with RA often develop joint destruction and deficits in muscle mass. The growth factor myostatin is a key regulator linking muscle mass and bone structure. We sou...

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Detalles Bibliográficos
Autores principales: Hu, Sung-Lin, Chang, An-Chen, Huang, Chien-Chung, Tsai, Chun-Hao, Lin, Cheng-Chieh, Tang, Chih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727021/
https://www.ncbi.nlm.nih.gov/pubmed/29276516
http://dx.doi.org/10.3389/fimmu.2017.01747

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