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cfDNA correlates with endothelial damage after cardiac surgery with prolonged cardiopulmonary bypass and amplifies NETosis in an intracellular TLR9-independent manner
Cardiopulmonary bypass (CPB) provokes inflammation culminating in organ dysfunction and increased mortality. Recently, neutrophil extracellular traps (NETs) have been found to be involved in a variety of cardiovascular diseases promoting tissue and organ injury. Here, we aimed to elaborate the proin...
Autores principales: | Paunel-Görgülü, Adnana, Wacker, Max, El Aita, Mouhamed, Hassan, Shoreshfan, Schlachtenberger, Georg, Deppe, Antje, Choi, Yeong-Hoon, Kuhn, Elmar, Mehler, Thorsten O., Wahlers, Thorsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727170/ https://www.ncbi.nlm.nih.gov/pubmed/29234042 http://dx.doi.org/10.1038/s41598-017-17561-1 |
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