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CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep

One of the ultimate goals of regenerative medicine is the generation of patient-specific organs from pluripotent stem cells (PSCs). Sheep are potential hosts for growing human organs through the technique of blastocyst complementation. We report here the creation of pancreatogenesis-disabled sheep b...

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Detalles Bibliográficos
Autores principales:	Vilarino, Marcela, Rashid, Sheikh Tamir, Suchy, Fabian Patrik, McNabb, Bret Roberts, van der Meulen, Talitha, Fine, Eli J., Ahsan, Syed Daniyal, Mursaliyev, Nurlybek, Sebastiano, Vittorio, Diab, Santiago Sain, Huising, Mark O., Nakauchi, Hiromitsu, Ross, Pablo J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727233/ https://www.ncbi.nlm.nih.gov/pubmed/29234093 http://dx.doi.org/10.1038/s41598-017-17805-0

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