Cargando…

Advantage of early orchiopexy for undescended testis: Analysis of testicular growth percentage ratio in patients with unilateral undescended testicle

This study reports the experience of our tertiary referral center and proposes a new indicator, the growth percentage ratio (GPR), for determining the optimal timing of surgical intervention. A retrospective review of boys who underwent orchiopexy for undescended testis from 2001 to 2013 was conduct...

Descripción completa

Detalles Bibliográficos
Autores principales: Tseng, Chi-Shin, Chiang, I-Ni, Hong, Chung-Hung, Lu, Yu-Chuan, Hong, Jian-Hua, Chang, Hong-Chiang, Huang, Kuo-How, Pu, Yeong-Shiau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727248/
https://www.ncbi.nlm.nih.gov/pubmed/29234092
http://dx.doi.org/10.1038/s41598-017-17825-w
_version_ 1783285840176218112
author Tseng, Chi-Shin
Chiang, I-Ni
Hong, Chung-Hung
Lu, Yu-Chuan
Hong, Jian-Hua
Chang, Hong-Chiang
Huang, Kuo-How
Pu, Yeong-Shiau
author_facet Tseng, Chi-Shin
Chiang, I-Ni
Hong, Chung-Hung
Lu, Yu-Chuan
Hong, Jian-Hua
Chang, Hong-Chiang
Huang, Kuo-How
Pu, Yeong-Shiau
author_sort Tseng, Chi-Shin
collection PubMed
description This study reports the experience of our tertiary referral center and proposes a new indicator, the growth percentage ratio (GPR), for determining the optimal timing of surgical intervention. A retrospective review of boys who underwent orchiopexy for undescended testis from 2001 to 2013 was conducted. We analyzed testicular volumes in different age groups using the UDT to normally descended testis ratio and testicular GPR. A total of 134 boys with unilateral undescended testicle underwent regular ultrasonography follow-up examinations for more than a mean of 3.9 years. Forty-five (33.4%) of them underwent orchiopexy before the age of one year. Orchiopexy at this age resulted in a GPR (2.02 ± 0.40) that was significantly higher than the GPRs in the second (1 < age ≤ 2 years, 1.25 ± 0.13, p = 0.004) and third (age > 2 years, 1.24 ± 0.14 p = 0.008) age groups. The undescended testicle grew faster when orchiopexy was performed before one year of age. Orchiopexy performed within one year from birth significantly accelerates the growth of the UDT, as determined using the GPR, compared to other age groups. The present clinical evidence indicates that orchiopexy should be performed before one year of age.
format Online
Article
Text
id pubmed-5727248
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-57272482017-12-13 Advantage of early orchiopexy for undescended testis: Analysis of testicular growth percentage ratio in patients with unilateral undescended testicle Tseng, Chi-Shin Chiang, I-Ni Hong, Chung-Hung Lu, Yu-Chuan Hong, Jian-Hua Chang, Hong-Chiang Huang, Kuo-How Pu, Yeong-Shiau Sci Rep Article This study reports the experience of our tertiary referral center and proposes a new indicator, the growth percentage ratio (GPR), for determining the optimal timing of surgical intervention. A retrospective review of boys who underwent orchiopexy for undescended testis from 2001 to 2013 was conducted. We analyzed testicular volumes in different age groups using the UDT to normally descended testis ratio and testicular GPR. A total of 134 boys with unilateral undescended testicle underwent regular ultrasonography follow-up examinations for more than a mean of 3.9 years. Forty-five (33.4%) of them underwent orchiopexy before the age of one year. Orchiopexy at this age resulted in a GPR (2.02 ± 0.40) that was significantly higher than the GPRs in the second (1 < age ≤ 2 years, 1.25 ± 0.13, p = 0.004) and third (age > 2 years, 1.24 ± 0.14 p = 0.008) age groups. The undescended testicle grew faster when orchiopexy was performed before one year of age. Orchiopexy performed within one year from birth significantly accelerates the growth of the UDT, as determined using the GPR, compared to other age groups. The present clinical evidence indicates that orchiopexy should be performed before one year of age. Nature Publishing Group UK 2017-12-12 /pmc/articles/PMC5727248/ /pubmed/29234092 http://dx.doi.org/10.1038/s41598-017-17825-w Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Tseng, Chi-Shin
Chiang, I-Ni
Hong, Chung-Hung
Lu, Yu-Chuan
Hong, Jian-Hua
Chang, Hong-Chiang
Huang, Kuo-How
Pu, Yeong-Shiau
Advantage of early orchiopexy for undescended testis: Analysis of testicular growth percentage ratio in patients with unilateral undescended testicle
title Advantage of early orchiopexy for undescended testis: Analysis of testicular growth percentage ratio in patients with unilateral undescended testicle
title_full Advantage of early orchiopexy for undescended testis: Analysis of testicular growth percentage ratio in patients with unilateral undescended testicle
title_fullStr Advantage of early orchiopexy for undescended testis: Analysis of testicular growth percentage ratio in patients with unilateral undescended testicle
title_full_unstemmed Advantage of early orchiopexy for undescended testis: Analysis of testicular growth percentage ratio in patients with unilateral undescended testicle
title_short Advantage of early orchiopexy for undescended testis: Analysis of testicular growth percentage ratio in patients with unilateral undescended testicle
title_sort advantage of early orchiopexy for undescended testis: analysis of testicular growth percentage ratio in patients with unilateral undescended testicle
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727248/
https://www.ncbi.nlm.nih.gov/pubmed/29234092
http://dx.doi.org/10.1038/s41598-017-17825-w
work_keys_str_mv AT tsengchishin advantageofearlyorchiopexyforundescendedtestisanalysisoftesticulargrowthpercentageratioinpatientswithunilateralundescendedtesticle
AT chiangini advantageofearlyorchiopexyforundescendedtestisanalysisoftesticulargrowthpercentageratioinpatientswithunilateralundescendedtesticle
AT hongchunghung advantageofearlyorchiopexyforundescendedtestisanalysisoftesticulargrowthpercentageratioinpatientswithunilateralundescendedtesticle
AT luyuchuan advantageofearlyorchiopexyforundescendedtestisanalysisoftesticulargrowthpercentageratioinpatientswithunilateralundescendedtesticle
AT hongjianhua advantageofearlyorchiopexyforundescendedtestisanalysisoftesticulargrowthpercentageratioinpatientswithunilateralundescendedtesticle
AT changhongchiang advantageofearlyorchiopexyforundescendedtestisanalysisoftesticulargrowthpercentageratioinpatientswithunilateralundescendedtesticle
AT huangkuohow advantageofearlyorchiopexyforundescendedtestisanalysisoftesticulargrowthpercentageratioinpatientswithunilateralundescendedtesticle
AT puyeongshiau advantageofearlyorchiopexyforundescendedtestisanalysisoftesticulargrowthpercentageratioinpatientswithunilateralundescendedtesticle