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POLE somatic mutations in advanced colorectal cancer

Despite all the knowledge already gathered, the picture of somatic genetic changes in colorectal tumorigenesis is far from complete. Recently, germline and somatic mutations in the exonuclease domain of polymerase epsilon, catalytic subunit (POLE) gene have been reported in a small subset of microsa...

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Detalles Bibliográficos
Autores principales:	Guerra, Joana, Pinto, Carla, Pinto, Diana, Pinheiro, Manuela, Silva, Romina, Peixoto, Ana, Rocha, Patrícia, Veiga, Isabel, Santos, Catarina, Santos, Rui, Cabreira, Verónica, Lopes, Paula, Henrique, Rui, Teixeira, Manuel R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727326/ https://www.ncbi.nlm.nih.gov/pubmed/29072370 http://dx.doi.org/10.1002/cam4.1245

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