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Molecular regulation and pharmacological targeting of the β‐catenin destruction complex

The β‐catenin destruction complex is a dynamic cytosolic multiprotein assembly that provides a key node in Wnt signalling regulation. The core components of the destruction complex comprise the scaffold proteins axin and adenomatous polyposis coli and the Ser/Thr kinases casein kinase 1 and glycogen...

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Detalles Bibliográficos
Autores principales:	van Kappel, Eline C, Maurice, Madelon M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Themed Section: Review Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727331/ https://www.ncbi.nlm.nih.gov/pubmed/28634996 http://dx.doi.org/10.1111/bph.13922

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