Cargando…
Treatment with Fenofibrate plus a low dose of Benznidazole attenuates cardiac dysfunction in experimental Chagas disease
Trypanosoma cruzi induces serious cardiac alterations during the chronic infection. Intense inflammatory response observed from the beginning of infection, is critical for the control of parasite proliferation and evolution of Chagas disease. Peroxisome proliferator-activated receptors (PPAR)-α, are...
Autores principales: | Cevey, Ágata C., Mirkin, Gerardo A., Donato, Martín, Rada, María J., Penas, Federico N., Gelpi, Ricardo J., Goren, Nora B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727348/ https://www.ncbi.nlm.nih.gov/pubmed/29040909 http://dx.doi.org/10.1016/j.ijpddr.2017.10.003 |
Ejemplares similares
-
IL-10-Dependent and -Independent Mechanisms Are Involved in the Cardiac Pathology Modulation Mediated by Fenofibrate in an Experimental Model of Chagas Heart Disease
por: Rada, Jimena, et al.
Publicado: (2020) -
Low-dose benznidazole treatment results in parasite clearance and attenuates heart inflammatory reaction in an experimental model of infection with a highly virulent Trypanosoma cruzi strain
por: Cevey, Ágata Carolina, et al.
Publicado: (2015) -
IL-10/STAT3/SOCS3 Axis Is Involved in the Anti-inflammatory Effect of Benznidazole
por: Cevey, Ágata C., et al.
Publicado: (2019) -
Fenofibrate Increases the Population of Non-Classical Monocytes in Asymptomatic Chagas Disease Patients and Modulates Inflammatory Cytokines in PBMC
por: Pieralisi, Azul V., et al.
Publicado: (2022) -
Benznidazole Anti-Inflammatory Effects in Murine Cardiomyocytes and Macrophages Are Mediated by Class I PI3Kδ
por: Cevey, Ágata C., et al.
Publicado: (2021)