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A pH-gated conformational switch regulates the phosphatase activity of bifunctional HisKA-family histidine kinases

Histidine kinases are key regulators in the bacterial two-component systems that mediate the cellular response to environmental changes. The vast majority of the sensor histidine kinases belong to the bifunctional HisKA family, displaying both kinase and phosphatase activities toward their substrate...

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Detalles Bibliográficos
Autores principales:	Liu, Yixiang, Rose, Joshua, Huang, Shaojia, Hu, Yangbo, Wu, Qiong, Wang, Dan, Li, Conggang, Liu, Maili, Zhou, Pei, Jiang, Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727384/ https://www.ncbi.nlm.nih.gov/pubmed/29235472 http://dx.doi.org/10.1038/s41467-017-02310-9

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