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Accumulation of long-term transcriptionally active integrated retroviral vectors in active promoters and enhancers
Most retroviruses preferentially integrate into certain genomic locations and, as a result, their genome-wide integration patterns are non-random. We investigate the epigenetic landscape of integrated retroviral vectors and correlate it with the long-term stability of proviral transcription. Retrovi...
Autores principales: | Šenigl, Filip, Miklík, Dalibor, Auxt, Miroslav, Hejnar, Jiří |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727404/ https://www.ncbi.nlm.nih.gov/pubmed/29244184 http://dx.doi.org/10.1093/nar/gkx889 |
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