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Independence between pre-mRNA splicing and DNA methylation in an isogenic minigene resource

Actively transcribed genes adopt a unique chromatin environment with characteristic patterns of enrichment. Within gene bodies, H3K36me3 and cytosine DNA methylation are elevated at exons of spliced genes and have been implicated in the regulation of pre-mRNA splicing. H3K36me3 is further responsive...

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Detalles Bibliográficos
Autores principales: Nanan, Kyster K., Ocheltree, Cody, Sturgill, David, Mandler, Mariana D., Prigge, Maria, Varma, Garima, Oberdoerffer, Shalini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727405/
https://www.ncbi.nlm.nih.gov/pubmed/29244186
http://dx.doi.org/10.1093/nar/gkx900