Rif1 promotes a repressive chromatin state to safeguard against endogenous retrovirus activation

Transposable elements, including endogenous retroviruses (ERVs), constitute a large fraction of the mammalian genome. They are transcriptionally silenced during early development to protect genome integrity and aberrant transcription. However, the mechanisms that control their repression are not ful...

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Detalles Bibliográficos
Autores principales: Li, Pishun, Wang, Li, Bennett, Brian D., Wang, Jiajia, Li, Jialun, Qin, Yufeng, Takaku, Motoki, Wade, Paul A., Wong, Jiemin, Hu, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727408/
https://www.ncbi.nlm.nih.gov/pubmed/29040764
http://dx.doi.org/10.1093/nar/gkx884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727408/
https://www.ncbi.nlm.nih.gov/pubmed/29040764
http://dx.doi.org/10.1093/nar/gkx884

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