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Prophages and Growth Dynamics Confound Experimental Results with Antibiotic-Tolerant Persister Cells

Bacterial persisters are phenotypic variants that survive antibiotic treatment in a dormant state and can be formed by multiple pathways. We recently proposed that the second messenger (p)ppGpp drives Escherichia coli persister formation through protease Lon and activation of toxin-antitoxin (TA) mo...

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Detalles Bibliográficos
Autores principales: Harms, Alexander, Fino, Cinzia, Sørensen, Michael A., Semsey, Szabolcs, Gerdes, Kenn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727415/
https://www.ncbi.nlm.nih.gov/pubmed/29233898
http://dx.doi.org/10.1128/mBio.01964-17