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Low-Density Lipoprotein Receptor Deficiency Attenuates Neuroinflammation through the Induction of Apolipoprotein E

OBJECTIVE: We aimed to determine the role of the low-density lipoprotein receptor (LDLr) in neuroinflammation by inducing experimental autoimmune encephalomyelitis (EAE) in ldlr knock out mice. METHODS: MOG(35–55) induced EAE in male and female ldlr(−/−) mice was assessed clinically and histopatholo...

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Detalles Bibliográficos
Autores principales:	Mailleux, Jo, Timmermans, Silke, Nelissen, Katherine, Vanmol, Jasmine, Vanmierlo, Tim, van Horssen, Jack, Bogie, Jeroen F. J., Hendriks, Jerome J. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727422/ https://www.ncbi.nlm.nih.gov/pubmed/29276512 http://dx.doi.org/10.3389/fimmu.2017.01701

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