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Generation and Functional In Vitro Analysis of Semliki Forest Virus Vectors Encoding TNF-α and IFN-γ

Cytokine gene delivery by viral vectors is a promising novel strategy for cancer immunotherapy. Semliki Forest virus (SFV) has many advantages as a delivery vector, including the ability to (i) induce p53-independent killing of tumor cells via apoptosis, (ii) elicit a type-I interferon (IFN) respons...

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Detalles Bibliográficos
Autores principales:	Kurena, Baiba, Müller, Elisabeth, Christopoulos, Panagiotis F., Johnsen, Ingvild Bjellmo, Stankovic, Branislava, Øynebråten, Inger, Corthay, Alexandre, Zajakina, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727424/ https://www.ncbi.nlm.nih.gov/pubmed/29276511 http://dx.doi.org/10.3389/fimmu.2017.01667

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