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Multiple RNA structures affect translation initiation and UGA redefinition efficiency during synthesis of selenoprotein P
Gene-specific expansion of the genetic code allows for UGA codons to specify the amino acid selenocysteine (Sec). A striking example of UGA redefinition occurs during translation of the mRNA coding for the selenium transport protein, selenoprotein P (SELENOP), which in vertebrates may contain up to...
Autores principales: | Mariotti, Marco, Shetty, Sumangala, Baird, Lisa, Wu, Sen, Loughran, Gary, Copeland, Paul R., Atkins, John F., Howard, Michael T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727441/ https://www.ncbi.nlm.nih.gov/pubmed/29069514 http://dx.doi.org/10.1093/nar/gkx982 |
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