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Design and implementation of a synthetic pre-miR switch for controlling miRNA biogenesis in mammals

Synthetic RNA-based systems have increasingly been used for the regulation of eukaryotic gene expression. Due to their structural properties, riboregulators provide a convenient basis for the development of ligand-dependent controllable systems. Here, we demonstrate reversible conditional control of...

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Detalles Bibliográficos
Autores principales: Atanasov, Janina, Groher, Florian, Weigand, Julia E., Suess, Beatrix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727447/
https://www.ncbi.nlm.nih.gov/pubmed/29036355
http://dx.doi.org/10.1093/nar/gkx858