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Design and implementation of a synthetic pre-miR switch for controlling miRNA biogenesis in mammals
Synthetic RNA-based systems have increasingly been used for the regulation of eukaryotic gene expression. Due to their structural properties, riboregulators provide a convenient basis for the development of ligand-dependent controllable systems. Here, we demonstrate reversible conditional control of...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727447/ https://www.ncbi.nlm.nih.gov/pubmed/29036355 http://dx.doi.org/10.1093/nar/gkx858 |