Weight Gain: A Possible Side Effect of All Antiretrovirals

Weight gain and body mass index (BMI) increase are central issues in patients living with HIV who need to minimize the risk of metabolic disease. Information collected through the SCOLTA cohort revealed significant 1-year BMI increase in patients treated with dolutegravir (P = .004), raltegravir (P...

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Autores principales: Taramasso, Lucia, Ricci, Elena, Menzaghi, Barbara, Orofino, Giancarlo, Passerini, Simone, Madeddu, Giordano, Martinelli, Canio Vito, De Socio, Giuseppe Vittorio, Squillace, Nicola, Rusconi, Stefano, Bonfanti, Paolo, Di Biagio, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727459/
https://www.ncbi.nlm.nih.gov/pubmed/29255735
http://dx.doi.org/10.1093/ofid/ofx239
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author Taramasso, Lucia
Ricci, Elena
Menzaghi, Barbara
Orofino, Giancarlo
Passerini, Simone
Madeddu, Giordano
Martinelli, Canio Vito
De Socio, Giuseppe Vittorio
Squillace, Nicola
Rusconi, Stefano
Bonfanti, Paolo
Di Biagio, Antonio
author_facet Taramasso, Lucia
Ricci, Elena
Menzaghi, Barbara
Orofino, Giancarlo
Passerini, Simone
Madeddu, Giordano
Martinelli, Canio Vito
De Socio, Giuseppe Vittorio
Squillace, Nicola
Rusconi, Stefano
Bonfanti, Paolo
Di Biagio, Antonio
author_sort Taramasso, Lucia
collection PubMed
description Weight gain and body mass index (BMI) increase are central issues in patients living with HIV who need to minimize the risk of metabolic disease. Information collected through the SCOLTA cohort revealed significant 1-year BMI increase in patients treated with dolutegravir (P = .004), raltegravir (P = .0004), elvitegravir (P = .004), darunavir (P = .0006), and rilpivirine (P = .029). BMI gain correlated with low baseline BMI (P = .002) and older age (P = .0007) in Centers for Disease Control and Prevention stages A/B, with lower BMI (P = .005) and CD4+ T-cell count (P = .007) at enrollment in stage C.
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spelling pubmed-57274592017-12-18 Weight Gain: A Possible Side Effect of All Antiretrovirals Taramasso, Lucia Ricci, Elena Menzaghi, Barbara Orofino, Giancarlo Passerini, Simone Madeddu, Giordano Martinelli, Canio Vito De Socio, Giuseppe Vittorio Squillace, Nicola Rusconi, Stefano Bonfanti, Paolo Di Biagio, Antonio Open Forum Infect Dis Brief Report Weight gain and body mass index (BMI) increase are central issues in patients living with HIV who need to minimize the risk of metabolic disease. Information collected through the SCOLTA cohort revealed significant 1-year BMI increase in patients treated with dolutegravir (P = .004), raltegravir (P = .0004), elvitegravir (P = .004), darunavir (P = .0006), and rilpivirine (P = .029). BMI gain correlated with low baseline BMI (P = .002) and older age (P = .0007) in Centers for Disease Control and Prevention stages A/B, with lower BMI (P = .005) and CD4+ T-cell count (P = .007) at enrollment in stage C. Oxford University Press 2017-11-03 /pmc/articles/PMC5727459/ /pubmed/29255735 http://dx.doi.org/10.1093/ofid/ofx239 Text en © The Author(s) 2017. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Taramasso, Lucia
Ricci, Elena
Menzaghi, Barbara
Orofino, Giancarlo
Passerini, Simone
Madeddu, Giordano
Martinelli, Canio Vito
De Socio, Giuseppe Vittorio
Squillace, Nicola
Rusconi, Stefano
Bonfanti, Paolo
Di Biagio, Antonio
Weight Gain: A Possible Side Effect of All Antiretrovirals
title Weight Gain: A Possible Side Effect of All Antiretrovirals
title_full Weight Gain: A Possible Side Effect of All Antiretrovirals
title_fullStr Weight Gain: A Possible Side Effect of All Antiretrovirals
title_full_unstemmed Weight Gain: A Possible Side Effect of All Antiretrovirals
title_short Weight Gain: A Possible Side Effect of All Antiretrovirals
title_sort weight gain: a possible side effect of all antiretrovirals
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727459/
https://www.ncbi.nlm.nih.gov/pubmed/29255735
http://dx.doi.org/10.1093/ofid/ofx239
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