An optogenetic arrhythmia model to study catecholaminergic polymorphic ventricular tachycardia mutations

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a condition of abnormal heart rhythm (arrhythmia), induced by physical activity or stress. Mutations in ryanodine receptor 2 (RyR2), a Ca(2+) release channel located in the sarcoplasmic reticulum (SR), or calsequestrin 2 (CASQ2), a SR C...

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Detalles Bibliográficos
Autores principales: Fischer, Elisabeth, Gottschalk, Alexander, Schüler, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727474/
https://www.ncbi.nlm.nih.gov/pubmed/29235522
http://dx.doi.org/10.1038/s41598-017-17819-8

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