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Leveraging ectopic Hsp90 expression to assay the presence of tumor cells and aggressive tumor phenotypes in breast specimens

Hsp90 has been studied extensively as a therapeutic target in breast cancer in pre-clinical and clinical trials, demonstrating a variety of roles in metastatic progression. The evidence to date suggests a compelling opportunity to leverage attributes of Hsp90 expression beyond therapeutics with pote...

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Detalles Bibliográficos
Autores principales: Crouch, Brian, Murphy, Helen, Belonwu, Stella, Martinez, Amy, Gallagher, Jennifer, Hall, Allison, Soo, Mary Scott, Lee, Marianne, Hughes, Philip, Haystead, Timothy, Ramanujam, Nirmala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727497/
https://www.ncbi.nlm.nih.gov/pubmed/29235516
http://dx.doi.org/10.1038/s41598-017-17832-x