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Leveraging ectopic Hsp90 expression to assay the presence of tumor cells and aggressive tumor phenotypes in breast specimens
Hsp90 has been studied extensively as a therapeutic target in breast cancer in pre-clinical and clinical trials, demonstrating a variety of roles in metastatic progression. The evidence to date suggests a compelling opportunity to leverage attributes of Hsp90 expression beyond therapeutics with pote...
Autores principales: | Crouch, Brian, Murphy, Helen, Belonwu, Stella, Martinez, Amy, Gallagher, Jennifer, Hall, Allison, Soo, Mary Scott, Lee, Marianne, Hughes, Philip, Haystead, Timothy, Ramanujam, Nirmala |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727497/ https://www.ncbi.nlm.nih.gov/pubmed/29235516 http://dx.doi.org/10.1038/s41598-017-17832-x |
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