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Association of MTHFR C677T and A1298C gene polymorphisms with methotrexate efficiency and toxicity in Algerian rheumatoid arthritis patients

Methotrexate (MTX) is the most used drug in rheumatoid arthritis (RA) treatment. However, it shows variability in clinical response, which is explained by an association with genetic polymorphisms. This study aimed to elucidate the role of the two gene polymorphism C677T and A1298C of the methylenet...

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Detalles Bibliográficos
Autores principales:	Berkani, Lilya M., Rahal, Fadia, Allam, Ines, Mouaki Benani, Soraya, Laadjouz, Aïcha, Djidjik, Reda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727549/ https://www.ncbi.nlm.nih.gov/pubmed/29264421 http://dx.doi.org/10.1016/j.heliyon.2017.e00467

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