Rare Cause of Recurrent Hypoglycemia: Insulin Autoimmune Syndrome

We report a case of insulin autoimmune syndrome associated with several autoantibodies, presenting with recurrent hypoglycemia, predominantly in the postprandial period, which improved by dietary management and spontaneously resolved within two months. Differentiation from other causes of hyperinsul...

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Autores principales: Tinmanee, Rungsima, Buranagan, Rungpailin, Ploybutr, Sirirat, Lertwattanarak, Raweewan, Sriwijitkamol, Apiradee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727552/
https://www.ncbi.nlm.nih.gov/pubmed/29318060
http://dx.doi.org/10.1155/2017/6423852
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author Tinmanee, Rungsima
Buranagan, Rungpailin
Ploybutr, Sirirat
Lertwattanarak, Raweewan
Sriwijitkamol, Apiradee
author_facet Tinmanee, Rungsima
Buranagan, Rungpailin
Ploybutr, Sirirat
Lertwattanarak, Raweewan
Sriwijitkamol, Apiradee
author_sort Tinmanee, Rungsima
collection PubMed
description We report a case of insulin autoimmune syndrome associated with several autoantibodies, presenting with recurrent hypoglycemia, predominantly in the postprandial period, which improved by dietary management and spontaneously resolved within two months. Differentiation from other causes of hyperinsulinemic hypoglycemia, such as insulinoma, is important to avoid unnecessary invasive procedures or surgical interventions. The 75-gram oral glucose tolerance test (OGTT) and mixed meal test showed a typical pattern, which may be useful indirect evidence of insulin autoimmune syndrome.
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spelling pubmed-57275522018-01-09 Rare Cause of Recurrent Hypoglycemia: Insulin Autoimmune Syndrome Tinmanee, Rungsima Buranagan, Rungpailin Ploybutr, Sirirat Lertwattanarak, Raweewan Sriwijitkamol, Apiradee Case Rep Endocrinol Case Report We report a case of insulin autoimmune syndrome associated with several autoantibodies, presenting with recurrent hypoglycemia, predominantly in the postprandial period, which improved by dietary management and spontaneously resolved within two months. Differentiation from other causes of hyperinsulinemic hypoglycemia, such as insulinoma, is important to avoid unnecessary invasive procedures or surgical interventions. The 75-gram oral glucose tolerance test (OGTT) and mixed meal test showed a typical pattern, which may be useful indirect evidence of insulin autoimmune syndrome. Hindawi 2017 2017-11-26 /pmc/articles/PMC5727552/ /pubmed/29318060 http://dx.doi.org/10.1155/2017/6423852 Text en Copyright © 2017 Rungsima Tinmanee et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Tinmanee, Rungsima
Buranagan, Rungpailin
Ploybutr, Sirirat
Lertwattanarak, Raweewan
Sriwijitkamol, Apiradee
Rare Cause of Recurrent Hypoglycemia: Insulin Autoimmune Syndrome
title Rare Cause of Recurrent Hypoglycemia: Insulin Autoimmune Syndrome
title_full Rare Cause of Recurrent Hypoglycemia: Insulin Autoimmune Syndrome
title_fullStr Rare Cause of Recurrent Hypoglycemia: Insulin Autoimmune Syndrome
title_full_unstemmed Rare Cause of Recurrent Hypoglycemia: Insulin Autoimmune Syndrome
title_short Rare Cause of Recurrent Hypoglycemia: Insulin Autoimmune Syndrome
title_sort rare cause of recurrent hypoglycemia: insulin autoimmune syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727552/
https://www.ncbi.nlm.nih.gov/pubmed/29318060
http://dx.doi.org/10.1155/2017/6423852
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