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Functional polymorphisms in asporin and CILP together with joint loading predispose to hand osteoarthritis
BACKGROUND: Osteoarthritis (OA) is the most common degenerative joint disease afflicting people in the Western world and has a strong genetic influence. The aim of this study was to examine the association of two known functional polymorphisms in the TGF-β inhibiting genes, asporin (ASPN) and cartil...
Autores principales: | Taipale, Mari, Solovieva, Svetlana, Leino-Arjas, Päivi, Männikkö, Minna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727665/ https://www.ncbi.nlm.nih.gov/pubmed/29233086 http://dx.doi.org/10.1186/s12863-017-0585-4 |
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