The clinical evaluation of platelet-rich plasma on free gingival graft's donor site wound healing

OBJECTIVE: It has been proved that platelet-rich plasma (PRP) can promote wound healing. In this way, PRP can be advantageous in periodontal plastic surgeries, free gingival graft (FGG) being one such surgery. MATERIALS AND METHODS: In this randomized split-mouth controlled trial, 10 patients who needed bilateral FGG were selected, and two donor sites were randomly assigned to experience either natural healing or healing-assisted with PRP. The outcome was assessed based on the comparison of the extent of wound closure, Manchester scale, Landry healing scale, visual analog scale, and tissue thickness between the study groups at different time intervals. STATISTICAL ANALYSIS USED: Repeated measurements of analysis of variance and paired t-test were used. Statistical significance was P ≤ 0.05. RESULTS: Significant differences between the study groups and also across different time intervals were seen in all parameters except for the changes in tissue thickness. CONCLUSION: PRP accelerates the healing process of wounds and reduces the healing time.