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The lncRNA MEG3 downregulation leads to osteoarthritis progression via miR-16/SMAD7 axis
BACKGROUND: Osteoarthritis (OA) is a chronic joint disease and there is no a definitive cure at present. Long non-coding RNAs (lncRNAs) have been confirmed to play important roles in the development of OA. However, the underlying mechanism of lncRNA maternally expressed gene 3 (MEG3) in OA has not b...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727780/ https://www.ncbi.nlm.nih.gov/pubmed/29255591 http://dx.doi.org/10.1186/s13578-017-0195-x |