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The human, F-actin-based cytoskeleton as a mutagen sensor
BACKGROUND: Forty years ago the actin cytoskeleton was determined to be disrupted in fibroblasts from persons with DNA repair-defective, hereditary colon cancer, with no clear connection between the cytoskeleton and DNA repair defects at that time. Recently, the large number of sequenced genomes has...
Autores principales: | Clark, Nicolette M., Garcia Galindo, Carlos A., Patel, Vandan K., Parry, Michele L., Stoll, Rebecca J., Yavorski, John M., Pinkason, Elizabeth P., Johnson, Edna M., Walker, Chelsea M., Johnson, Joseph, Sexton, Wade J., Coppola, Domenico, Blanck, George |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727871/ https://www.ncbi.nlm.nih.gov/pubmed/29255378 http://dx.doi.org/10.1186/s12935-017-0488-5 |
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