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Restoring synaptic plasticity and memory in mouse models of Alzheimer’s disease by PKR inhibition
Alzheimer’s disease (AD) is a neurodegenerative disorder associated with deficits in cognition and synaptic plasticity. While accumulation of amyloid β (Aβ) and hyper-phosphorylation of tau are parts of the etiology, AD can be caused by a large number of different genetic mutations and other unknown...
Autores principales: | Hwang, Kyoung-Doo, Bak, Myeong Seong, Kim, Sang Jeong, Rhee, Sangmyung, Lee, Yong-Seok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727890/ https://www.ncbi.nlm.nih.gov/pubmed/29233183 http://dx.doi.org/10.1186/s13041-017-0338-3 |
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