Neutrophil extracellular traps are downregulated by glucocorticosteroids in lungs in an equine model of asthma

BACKGROUND: Severe neutrophilic asthma is poorly responsive to glucocorticosteroids (GC). Neutrophil extracellular traps (NETs) within the lungs have been associated with the severity of airway obstruction and inflammation in asthma, and were found to be unaffected by GC in vitro. As IL-17 is overex...

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Detalles Bibliográficos
Autores principales: Vargas, Amandine, Boivin, Roxane, Cano, Patricia, Murcia, Yoana, Bazin, Isabelle, Lavoie, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727947/
https://www.ncbi.nlm.nih.gov/pubmed/29233147
http://dx.doi.org/10.1186/s12931-017-0689-4

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