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Sprifermin (rhFGF18) modulates extracellular matrix turnover in cartilage explants ex vivo

BACKGROUND: Sprifermin (recombinant human fibroblast growth factor 18) is in clinical development as a potential disease-modifying osteoarthritis drug (DMOAD). In vitro studies have shown that cartilage regenerative properties of sprifermin involve chondrocyte proliferation and extracellular matrix...

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Detalles Bibliográficos
Autores principales:	Reker, Ditte, Kjelgaard-Petersen, Cecilie F., Siebuhr, Anne Sofie, Michaelis, Martin, Gigout, Anne, Karsdal, Morten A., Ladel, Christoph, Bay-Jensen, Anne C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727954/ https://www.ncbi.nlm.nih.gov/pubmed/29233174 http://dx.doi.org/10.1186/s12967-017-1356-8

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