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Reference ranges for foetal nasal bone length, prenasal thickness, and interocular distance at 18 to 24 weeks’ gestation in low-risk pregnancies

BACKGROUND: The aim of the present study was to establish the normal ranges for foetal nasal bone length (NBL), prenasal skin thickness (PNT), interocular distance (IOD), and ratio of prenasal thickness to- nasal bone length (PNT/ NBL) at 18–24 weeks using two-dimensional (2D) ultrasound. METHODS: T...

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Autores principales: Altunkeser, Ayşegül, Körez, M. Kazım
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727986/
https://www.ncbi.nlm.nih.gov/pubmed/29233116
http://dx.doi.org/10.1186/s12884-017-1602-3
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author Altunkeser, Ayşegül
Körez, M. Kazım
author_facet Altunkeser, Ayşegül
Körez, M. Kazım
author_sort Altunkeser, Ayşegül
collection PubMed
description BACKGROUND: The aim of the present study was to establish the normal ranges for foetal nasal bone length (NBL), prenasal skin thickness (PNT), interocular distance (IOD), and ratio of prenasal thickness to- nasal bone length (PNT/ NBL) at 18–24 weeks using two-dimensional (2D) ultrasound. METHODS: This study was a retrospective study of prenatal ultrasonographic records from 407 foetuses between 18 and 24 weeks gestational age (GA). The NBL, PNT, IOD, PNT/ NBL ratio, biparietal diameter (BPD), and femur length (FL) were investigated. The relationships among NBL, PNT, IOD, PNT/ NBL, and GA were evaluated. Additionally, descriptive statistics for NBL, PNT, and IOD values for each gestational week were obtained. RESULTS: There was a significant association between GA and NBL, PNT, and IOD between 18 and 24 weeks. NBL increased from a mean of 5.5 mm to 8.3 mm, PNT increased from a mean of 3.5 mm to 5.1 mm, and IOD increased from a mean of 11.1 mm to 14.5 mm. PNT/NBL ratio did not change with gestational age. CONCLUSIONS: This study showed normal ranges for NBL, PNT, IOD, and PNT/ NBL ratios for foetuses between 18 and 24 weeks in low-risk pregnancies. There was a positive linear relationship between GA and NBL, PNT, and IOD. The PNT/NBL ratio might be a more useful measurement than NBL or PNT alone. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12884-017-1602-3) contains supplementary material, which is available to authorized users.
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spelling pubmed-57279862017-12-18 Reference ranges for foetal nasal bone length, prenasal thickness, and interocular distance at 18 to 24 weeks’ gestation in low-risk pregnancies Altunkeser, Ayşegül Körez, M. Kazım BMC Pregnancy Childbirth Research Article BACKGROUND: The aim of the present study was to establish the normal ranges for foetal nasal bone length (NBL), prenasal skin thickness (PNT), interocular distance (IOD), and ratio of prenasal thickness to- nasal bone length (PNT/ NBL) at 18–24 weeks using two-dimensional (2D) ultrasound. METHODS: This study was a retrospective study of prenatal ultrasonographic records from 407 foetuses between 18 and 24 weeks gestational age (GA). The NBL, PNT, IOD, PNT/ NBL ratio, biparietal diameter (BPD), and femur length (FL) were investigated. The relationships among NBL, PNT, IOD, PNT/ NBL, and GA were evaluated. Additionally, descriptive statistics for NBL, PNT, and IOD values for each gestational week were obtained. RESULTS: There was a significant association between GA and NBL, PNT, and IOD between 18 and 24 weeks. NBL increased from a mean of 5.5 mm to 8.3 mm, PNT increased from a mean of 3.5 mm to 5.1 mm, and IOD increased from a mean of 11.1 mm to 14.5 mm. PNT/NBL ratio did not change with gestational age. CONCLUSIONS: This study showed normal ranges for NBL, PNT, IOD, and PNT/ NBL ratios for foetuses between 18 and 24 weeks in low-risk pregnancies. There was a positive linear relationship between GA and NBL, PNT, and IOD. The PNT/NBL ratio might be a more useful measurement than NBL or PNT alone. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12884-017-1602-3) contains supplementary material, which is available to authorized users. BioMed Central 2017-12-12 /pmc/articles/PMC5727986/ /pubmed/29233116 http://dx.doi.org/10.1186/s12884-017-1602-3 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Altunkeser, Ayşegül
Körez, M. Kazım
Reference ranges for foetal nasal bone length, prenasal thickness, and interocular distance at 18 to 24 weeks’ gestation in low-risk pregnancies
title Reference ranges for foetal nasal bone length, prenasal thickness, and interocular distance at 18 to 24 weeks’ gestation in low-risk pregnancies
title_full Reference ranges for foetal nasal bone length, prenasal thickness, and interocular distance at 18 to 24 weeks’ gestation in low-risk pregnancies
title_fullStr Reference ranges for foetal nasal bone length, prenasal thickness, and interocular distance at 18 to 24 weeks’ gestation in low-risk pregnancies
title_full_unstemmed Reference ranges for foetal nasal bone length, prenasal thickness, and interocular distance at 18 to 24 weeks’ gestation in low-risk pregnancies
title_short Reference ranges for foetal nasal bone length, prenasal thickness, and interocular distance at 18 to 24 weeks’ gestation in low-risk pregnancies
title_sort reference ranges for foetal nasal bone length, prenasal thickness, and interocular distance at 18 to 24 weeks’ gestation in low-risk pregnancies
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727986/
https://www.ncbi.nlm.nih.gov/pubmed/29233116
http://dx.doi.org/10.1186/s12884-017-1602-3
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