Association between long interspersed nuclear element-1 methylation levels and relapse in Wilms tumors

BACKGROUND: Wilms tumor (WT) is a curable pediatric renal malignancy, but there is a need for new molecular biomarkers to improve relapse risk-directed therapy. Somatic alterations occur at relatively low frequencies whereas epigenetic changes at 11p15 are the most common aberration. We analyzed lon...

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Detalles Bibliográficos
Autores principales: de Sá Pereira, Bruna M., Montalvão-de-Azevedo, Rafaela, Faria, Paulo Antônio, de Paula Silva, Neimar, Nicolau-Neto, Pedro, Maschietto, Mariana, de Camargo, Beatriz, Soares Lima, Sheila Coelho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728012/
https://www.ncbi.nlm.nih.gov/pubmed/29255497
http://dx.doi.org/10.1186/s13148-017-0431-6

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