Development of Molecularly Driven Targeted Combination Strategies

Targeted therapies are often inadequate when used in isolation as single agents. Combining diverse targeted therapies could optimally impact patient care by overcoming cancer resistance mechanisms. This commentary highlights such combinatorial strategies, including discussion on a recent trial.

Detalles Bibliográficos
Autores principales: Yap, Timothy A., Rodon, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AlphaMed Press 2017
Materias:
Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728037/
https://www.ncbi.nlm.nih.gov/pubmed/29038233
http://dx.doi.org/10.1634/theoncologist.2017-0402
_version_ 1783285999490564096
author Yap, Timothy A.
Rodon, Jordi
author_facet Yap, Timothy A.
Rodon, Jordi
author_sort Yap, Timothy A.
collection PubMed
description Targeted therapies are often inadequate when used in isolation as single agents. Combining diverse targeted therapies could optimally impact patient care by overcoming cancer resistance mechanisms. This commentary highlights such combinatorial strategies, including discussion on a recent trial.
format Online
Article
Text
id pubmed-5728037
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher AlphaMed Press
record_format MEDLINE/PubMed
spelling pubmed-57280372017-12-17 Development of Molecularly Driven Targeted Combination Strategies Yap, Timothy A. Rodon, Jordi Oncologist Commentaries Targeted therapies are often inadequate when used in isolation as single agents. Combining diverse targeted therapies could optimally impact patient care by overcoming cancer resistance mechanisms. This commentary highlights such combinatorial strategies, including discussion on a recent trial. AlphaMed Press 2017-10-16 2017-12 /pmc/articles/PMC5728037/ /pubmed/29038233 http://dx.doi.org/10.1634/theoncologist.2017-0402 Text en © AlphaMed Press 2017
spellingShingle Commentaries
Yap, Timothy A.
Rodon, Jordi
Development of Molecularly Driven Targeted Combination Strategies
title Development of Molecularly Driven Targeted Combination Strategies
title_full Development of Molecularly Driven Targeted Combination Strategies
title_fullStr Development of Molecularly Driven Targeted Combination Strategies
title_full_unstemmed Development of Molecularly Driven Targeted Combination Strategies
title_short Development of Molecularly Driven Targeted Combination Strategies
title_sort development of molecularly driven targeted combination strategies
topic Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728037/
https://www.ncbi.nlm.nih.gov/pubmed/29038233
http://dx.doi.org/10.1634/theoncologist.2017-0402
work_keys_str_mv AT yaptimothya developmentofmolecularlydriventargetedcombinationstrategies
AT rodonjordi developmentofmolecularlydriventargetedcombinationstrategies

Ejemplares similares