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The gene–treatment interaction of paraoxonase-1 gene polymorphism and statin therapy on insulin secretion in Japanese patients with type 2 diabetes: Fukuoka diabetes registry
BACKGROUND: Although statins deteriorate glucose metabolism, their glucose-lowering effects have emerged in some situations. Here, we assessed whether these effects are a consequence of statins’ interaction with paraoxonase (PON)1 enzyme polymorphism. METHODS: Adult Japanese type 2 diabetes patients...
Autores principales: | Sumi, Akiko, Nakamura, Udai, Iwase, Masanori, Fujii, Hiroki, Ohkuma, Toshiaki, Ide, Hitoshi, Jodai-Kitamura, Tamaki, Komorita, Yuji, Yoshinari, Masahito, Hirakawa, Yoichiro, Hirano, Atsushi, Kubo, Michiaki, Kitazono, Takanari |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728066/ https://www.ncbi.nlm.nih.gov/pubmed/29233102 http://dx.doi.org/10.1186/s12881-017-0509-1 |
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