Cargando…

Secondary structure forming sequences drive SD-MMEJ repair of DNA double-strand breaks

Alternative end-joining (alt-EJ) repair of DNA double-strand breaks is associated with deletions, chromosome translocations, and genome instability. Alt-EJ frequently uses annealing of microhomologous sequences to tether broken ends. When accessible pre-existing microhomologies do not exist, we have...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khodaverdian, Varandt Y., Hanscom, Terrence, Yu, Amy Marie, Yu, Taylor L., Mak, Victoria, Brown, Alexander J., Roberts, Steven A., McVey, Mitch
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728401/ https://www.ncbi.nlm.nih.gov/pubmed/29121353 http://dx.doi.org/10.1093/nar/gkx1056

Ejemplares similares

Characterization of sequence contexts that favor alternative end joining at Cas9-induced double-strand breaks
por: Hanscom, Terrence, et al.
Publicado: (2022)

Synthesis-dependent microhomology-mediated end joining accounts for multiple types of repair junctions
por: Yu, Amy Marie, et al.
Publicado: (2010)

Dynamics and competition of CRISPR–Cas9 ribonucleoproteins and AAV donor-mediated NHEJ, MMEJ and HDR editing
por: Fu, Ya-Wen, et al.
Publicado: (2021)

CTCF cooperates with CtIP to drive homologous recombination repair of double-strand breaks
por: Hwang, Soon Young, et al.
Publicado: (2019)

DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair
por: Abdou, Ismail, et al.
Publicado: (2015)

Pathological mutations in PNKP trigger defects in DNA single-strand break repair but not DNA double-strand break repair
por: Kalasova, Ilona, et al.
Publicado: (2020)

Conservation and divergence of meiotic DNA double strand break forming mechanisms in Arabidopsis thaliana
por: Vrielynck, Nathalie, et al.
Publicado: (2021)

Double-strand break toxicity is chromatin context independent
por: Friskes, Anoek, et al.
Publicado: (2022)

Mechanistic analysis of Xenopus EXO1's function in 5′-strand resection at DNA double-strand breaks
por: Liao, Shuren, et al.
Publicado: (2011)

Human RECQ5 helicase promotes repair of DNA double-strand breaks by synthesis-dependent strand annealing
por: Paliwal, Shreya, et al.
Publicado: (2014)

ARF induction in response to DNA strand breaks is regulated by PARP1
por: Orlando, Giulia, et al.
Publicado: (2014)

A double-strand break can trigger immunoglobulin gene conversion
por: Bastianello, Giulia, et al.
Publicado: (2017)

Dna2 initiates resection at clean DNA double-strand breaks
por: Paudyal, Sharad C., et al.
Publicado: (2017)

Hedgehog signaling enables repair of ribosomal DNA double-strand breaks
por: Lama-Sherpa, Tshering D, et al.
Publicado: (2020)

APE1 senses DNA single-strand breaks for repair and signaling
por: Lin, Yunfeng, et al.
Publicado: (2020)

Evidence that MEK1 positively promotes interhomologue double-strand break repair
por: Terentyev, Yaroslav, et al.
Publicado: (2010)

A moonlighting metabolic protein influences repair at DNA double-stranded breaks
por: Torres-Machorro, Ana Lilia, et al.
Publicado: (2015)

Smarcal1 promotes double-strand-break repair by nonhomologous end-joining
por: Keka, Islam Shamima, et al.
Publicado: (2015)

The COP9 signalosome is vital for timely repair of DNA double-strand breaks
por: Meir, Michal, et al.
Publicado: (2015)

Evidence for double-strand break mediated mitochondrial DNA replication in Saccharomyces cerevisiae
por: Prasai, Kanchanjunga, et al.
Publicado: (2017)

Topoisomerase II contributes to DNA secondary structure-mediated double-stranded breaks
por: Szlachta, Karol, et al.
Publicado: (2020)

Single-strand nicks induce homologous recombination with less toxicity than double-strand breaks using an AAV vector template
por: Metzger, Michael J., et al.
Publicado: (2011)

Single-stranded DNA oligomers stimulate error-prone alternative repair of DNA double-strand breaks through hijacking Ku protein
por: Yuan, Ying, et al.
Publicado: (2015)

Super-resolution imaging identifies PARP1 and the Ku complex acting as DNA double-strand break sensors
por: Yang, Guang, et al.
Publicado: (2018)

Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks
por: Bolderson, Emma, et al.
Publicado: (2010)

Cellular responses to DNA double-strand breaks after low-dose γ-irradiation
por: Asaithamby, Aroumougame, et al.
Publicado: (2009)

GEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombination
por: Takizawa, Yoshimasa, et al.
Publicado: (2010)

Analysis of MRE11's function in the 5′→3′ processing of DNA double-strand breaks
por: Liao, Shuren, et al.
Publicado: (2012)

The 9-1-1 checkpoint clamp coordinates resection at DNA double strand breaks
por: Ngo, Greg H.P., et al.
Publicado: (2015)

Recombinational repair of radiation-induced double-strand breaks occurs in the absence of extensive resection
por: Westmoreland, James W., et al.
Publicado: (2016)

Processing by MRE11 is involved in the sensitivity of subtelomeric regions to DNA double-strand breaks
por: Muraki, Keiko, et al.
Publicado: (2015)

Acetylation of 53BP1 dictates the DNA double strand break repair pathway
por: Guo, Xiang, et al.
Publicado: (2018)

Mechanism of efficient double-strand break repair by a long non-coding RNA
por: Thapar, Roopa, et al.
Publicado: (2020)

Regulation of Error-Prone DNA Double-Strand Break Repair and Its Impact on Genome Evolution
por: Hanscom, Terrence, et al.
Publicado: (2020)

Homologous recombination repair intermediates promote efficient de novo telomere addition at DNA double-strand breaks
por: Davé, Anoushka, et al.
Publicado: (2020)

Distinct genetic control of homologous recombination repair of Cas9-induced double-strand breaks, nicks and paired nicks
por: Vriend, Lianne E.M., et al.
Publicado: (2016)

Cohesin promotes the repair of ionizing radiation-induced DNA double-strand breaks in replicated chromatin
por: Bauerschmidt, Christina, et al.
Publicado: (2010)

Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks
por: Cheng, Qiao, et al.
Publicado: (2011)

Radiation-induced double-strand breaks require ATM but not Artemis for homologous recombination during S-phase
por: Köcher, Sabrina, et al.
Publicado: (2012)

p21 promotes error-free replication-coupled DNA double-strand break repair
por: Mauro, Maurizio, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_knj7nupo1mvc5sjhuorf136l24