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Discovering cancer vulnerabilities using high-throughput micro-RNA screening

Micro-RNAs (miRNAs) are potent regulators of gene expression and cellular phenotype. Each miRNA has the potential to target hundreds of transcripts within the cell thus controlling fundamental cellular processes such as survival and proliferation. Here, we exploit this important feature of miRNA net...

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Detalles Bibliográficos
Autores principales: Nikolic, Iva, Elsworth, Benjamin, Dodson, Eoin, Wu, Sunny Z., Gould, Cathryn M., Mestdagh, Pieter, Marshall, Glenn M., Horvath, Lisa G., Simpson, Kaylene J., Swarbrick, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728403/
https://www.ncbi.nlm.nih.gov/pubmed/29156009
http://dx.doi.org/10.1093/nar/gkx1072