Discovering the 3′ UTR-mediated regulation of alpha-synuclein

Recent evidence indicates a link between Parkinson's Disease (PD) and the expression of a-synuclein (SNCA) isoforms with different 3′ untranslated regions (3′UTRs). Yet, the post-transcriptional mechanisms regulating SNCA expression are unknown. Using a large-scale in vitro /in silico screening...

Descripción completa

Detalles Bibliográficos
Autores principales: Marchese, Domenica, Botta-Orfila, Teresa, Cirillo, Davide, Rodriguez, Juan Antonio, Livi, Carmen Maria, Fernández-Santiago, Rubén, Ezquerra, Mario, Martí, Maria J, Bechara, Elias, Tartaglia, Gian Gaetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728410/
https://www.ncbi.nlm.nih.gov/pubmed/29149290
http://dx.doi.org/10.1093/nar/gkx1048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728410/
https://www.ncbi.nlm.nih.gov/pubmed/29149290
http://dx.doi.org/10.1093/nar/gkx1048

Ejemplares similares