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The mechano-chemistry of a monomeric reverse transcriptase

Retroviral reverse transcriptase catalyses the synthesis of an integration-competent dsDNA molecule, using as a substrate the viral RNA. Using optical tweezers, we follow the Murine Leukemia Virus reverse transcriptase as it performs strand-displacement polymerization on a template under mechanical...

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Detalles Bibliográficos
Autores principales:	Malik, Omri, Khamis, Hadeel, Rudnizky, Sergei, Kaplan, Ariel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728418/ https://www.ncbi.nlm.nih.gov/pubmed/29165701 http://dx.doi.org/10.1093/nar/gkx1168

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