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Interleukin-35 mitigates the function of murine transplanted islet cells via regulation of Treg/Th17 ratio

Pancreatic islet transplantation is a promising treatment for type 1 diabetes (T1D). Interleukin-35 (IL-35) is a recently discovered cytokine that exhibits potent immunosuppressive functions. However, the role of IL-35 in islet transplant rejection remains to be elucidated. In this study, we isolate...

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Detalles Bibliográficos
Autores principales:	Zongyi, Yin, Funian, Zou, Hao, Li, Xin, Wang, Ying, Cheng, Jialin, Zhang, Yongfeng, Liu, Baifeng, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728515/ https://www.ncbi.nlm.nih.gov/pubmed/29236782 http://dx.doi.org/10.1371/journal.pone.0189617

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