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Identification of GAD65 AA 114-122 reactive 'memory-like' NK cells in newly diagnosed Type 1 diabetic patients by HLA-class I pentamers
Type 1 diabetes is an autoimmune disease, in which pancreatic β cells are destroyed by autoreactive T cells in genetically predisposed individuals. Serum beta cell autoantibody specificities have represented the mainstay for classifying diabetes as autoimmune-mediated and for stratifying risk in fir...
Autores principales: | Perri, Valentina, Gianchecchi, Elena, Cifaldi, Loredana, Pellegrino, Marsha, Giorda, Ezio, Andreani, Marco, Cappa, Marco, Fierabracci, Alessandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728516/ https://www.ncbi.nlm.nih.gov/pubmed/29236750 http://dx.doi.org/10.1371/journal.pone.0189615 |
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