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DDM1 and Lsh remodelers allow methylation of DNA wrapped in nucleosomes

Cytosine methylation regulates essential genome functions across eukaryotes, but the fundamental question of whether nucleosomal or naked DNA is the preferred substrate of plant and animal methyltransferases remains unresolved. Here, we show that genetic inactivation of a single DDM1/Lsh family nucl...

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Detalles Bibliográficos
Autores principales: Lyons, David B, Zilberman, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728721/
https://www.ncbi.nlm.nih.gov/pubmed/29140247
http://dx.doi.org/10.7554/eLife.30674