Cargando…

Epithelial-myoepithelial carcinoma with high-grade transformation of parotid gland: A case report and literature review

RATIONALE: Epithelial-myoepithelial carcinoma (EMC) is regarded as a rare low-grade malignant tumor of the salivary gland, accounting for 0.4% to 1% of all salivary gland tumors. However, epithelial-myoepithelial carcinoma with high-grade transformation (EMC with HGT) is extremely rare, therefore it...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Bowen, Yang, Hongyu, Hong, Xia, Wang, Yufan, Wang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728887/
https://www.ncbi.nlm.nih.gov/pubmed/29245272
http://dx.doi.org/10.1097/MD.0000000000008988
_version_ 1783286101022081024
author Li, Bowen
Yang, Hongyu
Hong, Xia
Wang, Yufan
Wang, Feng
author_facet Li, Bowen
Yang, Hongyu
Hong, Xia
Wang, Yufan
Wang, Feng
author_sort Li, Bowen
collection PubMed
description RATIONALE: Epithelial-myoepithelial carcinoma (EMC) is regarded as a rare low-grade malignant tumor of the salivary gland, accounting for 0.4% to 1% of all salivary gland tumors. However, epithelial-myoepithelial carcinoma with high-grade transformation (EMC with HGT) is extremely rare, therefore it is easily to be inappropriately diagnosed and treated. Herein, we report an unusual case of EMC with HGT involving the parotid gland and discuss the clinical features and histological characteristic of EMC with HGT, in order to remind the doctors to take appropriate diagnosis and treatment. PATIENT CONCERNS: A 77-year-old female sought for treatment in our hospital due to pain mass in the left parotid gland for 6 months with rapid growth recently. DIAGNOSES: EMC with HGT was confirmed by final pathology, and then the result showed there were 2 distinctly different areas in the tumor, including the typical EMC component and intensive spindle cells component. INTERVENTIONS: The extensive resection surgery was performed. OUTCOMES: The patient was uneventful after surgery and no recurrence or metastasis has been observed after follow-up of 4 years. LESSONS: A review of literature suggested that EMC with HGT patients trend to be more aged, more aggressive and poorer prognosis than typical EMC patients. In order to avoid misdiagnosis and inappropriate treatment, it is necessary to accurately recognize the differences between the EMC with HGT and typical EMC.
format Online
Article
Text
id pubmed-5728887
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Wolters Kluwer Health
record_format MEDLINE/PubMed
spelling pubmed-57288872017-12-20 Epithelial-myoepithelial carcinoma with high-grade transformation of parotid gland: A case report and literature review Li, Bowen Yang, Hongyu Hong, Xia Wang, Yufan Wang, Feng Medicine (Baltimore) 5900 RATIONALE: Epithelial-myoepithelial carcinoma (EMC) is regarded as a rare low-grade malignant tumor of the salivary gland, accounting for 0.4% to 1% of all salivary gland tumors. However, epithelial-myoepithelial carcinoma with high-grade transformation (EMC with HGT) is extremely rare, therefore it is easily to be inappropriately diagnosed and treated. Herein, we report an unusual case of EMC with HGT involving the parotid gland and discuss the clinical features and histological characteristic of EMC with HGT, in order to remind the doctors to take appropriate diagnosis and treatment. PATIENT CONCERNS: A 77-year-old female sought for treatment in our hospital due to pain mass in the left parotid gland for 6 months with rapid growth recently. DIAGNOSES: EMC with HGT was confirmed by final pathology, and then the result showed there were 2 distinctly different areas in the tumor, including the typical EMC component and intensive spindle cells component. INTERVENTIONS: The extensive resection surgery was performed. OUTCOMES: The patient was uneventful after surgery and no recurrence or metastasis has been observed after follow-up of 4 years. LESSONS: A review of literature suggested that EMC with HGT patients trend to be more aged, more aggressive and poorer prognosis than typical EMC patients. In order to avoid misdiagnosis and inappropriate treatment, it is necessary to accurately recognize the differences between the EMC with HGT and typical EMC. Wolters Kluwer Health 2017-12-08 /pmc/articles/PMC5728887/ /pubmed/29245272 http://dx.doi.org/10.1097/MD.0000000000008988 Text en Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0
spellingShingle 5900
Li, Bowen
Yang, Hongyu
Hong, Xia
Wang, Yufan
Wang, Feng
Epithelial-myoepithelial carcinoma with high-grade transformation of parotid gland: A case report and literature review
title Epithelial-myoepithelial carcinoma with high-grade transformation of parotid gland: A case report and literature review
title_full Epithelial-myoepithelial carcinoma with high-grade transformation of parotid gland: A case report and literature review
title_fullStr Epithelial-myoepithelial carcinoma with high-grade transformation of parotid gland: A case report and literature review
title_full_unstemmed Epithelial-myoepithelial carcinoma with high-grade transformation of parotid gland: A case report and literature review
title_short Epithelial-myoepithelial carcinoma with high-grade transformation of parotid gland: A case report and literature review
title_sort epithelial-myoepithelial carcinoma with high-grade transformation of parotid gland: a case report and literature review
topic 5900
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728887/
https://www.ncbi.nlm.nih.gov/pubmed/29245272
http://dx.doi.org/10.1097/MD.0000000000008988
work_keys_str_mv AT libowen epithelialmyoepithelialcarcinomawithhighgradetransformationofparotidglandacasereportandliteraturereview
AT yanghongyu epithelialmyoepithelialcarcinomawithhighgradetransformationofparotidglandacasereportandliteraturereview
AT hongxia epithelialmyoepithelialcarcinomawithhighgradetransformationofparotidglandacasereportandliteraturereview
AT wangyufan epithelialmyoepithelialcarcinomawithhighgradetransformationofparotidglandacasereportandliteraturereview
AT wangfeng epithelialmyoepithelialcarcinomawithhighgradetransformationofparotidglandacasereportandliteraturereview