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Elevated 18F-NaF uptake in cricoid cartilage in a patient with laryngeal carcinoma: A case report and literature review

RATIONALE: Laryngeal cancer is aggressive tumor that arises from the tissues of the larynx. Although any bone can be affected, involvement of cricoid cartilage was reported very rarely, and there has been no report of 18F-sodium fluoride positron emission tomography-computed tomography ((18)F-NaF PE...

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Autores principales: Xia, Yuxiao, Qi, Chi, Zhang, Shumao, Huang, Zhanwen, Chen, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728947/
https://www.ncbi.nlm.nih.gov/pubmed/29245332
http://dx.doi.org/10.1097/MD.0000000000009090
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author Xia, Yuxiao
Qi, Chi
Zhang, Shumao
Huang, Zhanwen
Chen, Yue
author_facet Xia, Yuxiao
Qi, Chi
Zhang, Shumao
Huang, Zhanwen
Chen, Yue
author_sort Xia, Yuxiao
collection PubMed
description RATIONALE: Laryngeal cancer is aggressive tumor that arises from the tissues of the larynx. Although any bone can be affected, involvement of cricoid cartilage was reported very rarely, and there has been no report of 18F-sodium fluoride positron emission tomography-computed tomography ((18)F-NaF PET-CT) and 3D PET-CT for the evaluation of cricoid cartilage invasion. PATIENT CONCERNS: A 54-year-old male discovered a protruding mass in the right anterior neck, which had rapidly increased in size over a period of 2 months. Subsequently, hoarseness, dysphagia, and dyspnea were gradually developed. DIAGNOSES: (18)F-FDG PET-CT demonstrated that the abnormal activity was located in a soft tissue mass, which was about 4.2 cm × 3.8 cm × 3.6 cm in largest dimension in the laryngeal cavity of supraglottic portion (SUVmax: 23.6). A swollen lymph node was revealed in the right submandibular region, which had intense FDG activity with a SUVmax of 18.4. However, there is a high uptake of (18)F-FDG in the region near the bone, which is uncertain whether there is any skeletal invasion. NaF PET-CT and 3D PET-CT demonstrated increased uptake in the right side of cricoid cartilage (SUVmax: 13.2). The histopathologic examination confirmed squamous cell carcinoma of larynx. INTERVENTIONS: The patient underwent tracheotomy and received anti-infective treatment to relieve symptoms of dyspnea and prevent asphyxia. OUTCOMES: Clinical follow up of the patient revealed that dyspnea was significantly relieved. LESSONS: The case report shows the imaging features of cricoid cartilage invasion, including (18)F-FDG PET/CT, 18F-sodium fluoride positron emission tomography-computed tomography ((18)F-NaF PET-CT), and 3D PET-CT. Precise understanding of the invasion scope, accurately staging of laryngeal carcinoma, and choosing of the most suitable surgical scheme are the factors that lead to the optimal treatment of laryngeal neoplasms.
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spelling pubmed-57289472017-12-20 Elevated 18F-NaF uptake in cricoid cartilage in a patient with laryngeal carcinoma: A case report and literature review Xia, Yuxiao Qi, Chi Zhang, Shumao Huang, Zhanwen Chen, Yue Medicine (Baltimore) 6800 RATIONALE: Laryngeal cancer is aggressive tumor that arises from the tissues of the larynx. Although any bone can be affected, involvement of cricoid cartilage was reported very rarely, and there has been no report of 18F-sodium fluoride positron emission tomography-computed tomography ((18)F-NaF PET-CT) and 3D PET-CT for the evaluation of cricoid cartilage invasion. PATIENT CONCERNS: A 54-year-old male discovered a protruding mass in the right anterior neck, which had rapidly increased in size over a period of 2 months. Subsequently, hoarseness, dysphagia, and dyspnea were gradually developed. DIAGNOSES: (18)F-FDG PET-CT demonstrated that the abnormal activity was located in a soft tissue mass, which was about 4.2 cm × 3.8 cm × 3.6 cm in largest dimension in the laryngeal cavity of supraglottic portion (SUVmax: 23.6). A swollen lymph node was revealed in the right submandibular region, which had intense FDG activity with a SUVmax of 18.4. However, there is a high uptake of (18)F-FDG in the region near the bone, which is uncertain whether there is any skeletal invasion. NaF PET-CT and 3D PET-CT demonstrated increased uptake in the right side of cricoid cartilage (SUVmax: 13.2). The histopathologic examination confirmed squamous cell carcinoma of larynx. INTERVENTIONS: The patient underwent tracheotomy and received anti-infective treatment to relieve symptoms of dyspnea and prevent asphyxia. OUTCOMES: Clinical follow up of the patient revealed that dyspnea was significantly relieved. LESSONS: The case report shows the imaging features of cricoid cartilage invasion, including (18)F-FDG PET/CT, 18F-sodium fluoride positron emission tomography-computed tomography ((18)F-NaF PET-CT), and 3D PET-CT. Precise understanding of the invasion scope, accurately staging of laryngeal carcinoma, and choosing of the most suitable surgical scheme are the factors that lead to the optimal treatment of laryngeal neoplasms. Wolters Kluwer Health 2017-12-08 /pmc/articles/PMC5728947/ /pubmed/29245332 http://dx.doi.org/10.1097/MD.0000000000009090 Text en Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nd/4.0 This is an open access article distributed under the Creative Commons Attribution-NoDerivatives License 4.0, which allows for redistribution, commercial and non-commercial, as long as it is passed along unchanged and in whole, with credit to the author. http://creativecommons.org/licenses/by-nd/4.0
spellingShingle 6800
Xia, Yuxiao
Qi, Chi
Zhang, Shumao
Huang, Zhanwen
Chen, Yue
Elevated 18F-NaF uptake in cricoid cartilage in a patient with laryngeal carcinoma: A case report and literature review
title Elevated 18F-NaF uptake in cricoid cartilage in a patient with laryngeal carcinoma: A case report and literature review
title_full Elevated 18F-NaF uptake in cricoid cartilage in a patient with laryngeal carcinoma: A case report and literature review
title_fullStr Elevated 18F-NaF uptake in cricoid cartilage in a patient with laryngeal carcinoma: A case report and literature review
title_full_unstemmed Elevated 18F-NaF uptake in cricoid cartilage in a patient with laryngeal carcinoma: A case report and literature review
title_short Elevated 18F-NaF uptake in cricoid cartilage in a patient with laryngeal carcinoma: A case report and literature review
title_sort elevated 18f-naf uptake in cricoid cartilage in a patient with laryngeal carcinoma: a case report and literature review
topic 6800
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728947/
https://www.ncbi.nlm.nih.gov/pubmed/29245332
http://dx.doi.org/10.1097/MD.0000000000009090
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