Influence of proton pump inhibitors on blood dabigatran concentrations in Japanese patients with non-valvular atrial fibrillation

BACKGROUND: Dabigatran is a direct thrombin inhibitor used to decrease the risk of ischemic stroke in patients with non-valvular atrial fibrillation (NVAF). Its prodrug, dabigatran etexilate (DE) is often co-administrated with a proton pump inhibitor (PPI) because of its adverse effects on the gastr...

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Detalles Bibliográficos
Autores principales: Kuwayama, Tasuku, Osanai, Hiroyuki, Ajioka, Masayoshi, Tokuda, Kotaro, Ohashi, Hirofumi, Tobe, Akihiro, Yoshida, Tatsuya, Masutomi, Tomohiro, Kambara, Takahiro, Inoue, Yosuke, Nakashima, Yoshihito, Asano, Hiroshi, Sakai, Kazuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729000/
https://www.ncbi.nlm.nih.gov/pubmed/29255511
http://dx.doi.org/10.1016/j.joa.2017.07.013

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